TY - JOUR
T1 - In vitro activities of an investigational quinolone, glycylcycline, glycopeptide, streptogramin, and oxazolidinone tested alone and in combinations against vancomycin-resistant Enterococcus faecium
AU - Mercier, Renee Claude
AU - Penzak, Scott R.
AU - Rybak, Michael J.
PY - 1997/11
Y1 - 1997/11
N2 - We evaluated the in vitro activities of clinafloxacin, CL331,002, LY333328, quinupristin dalfopristin, and eperezolid (formerly known as U- 100,592) against four strains of enterococci. All regimens tested resulted in the growth inhibition of each isolate. Against the three clinafloxacin- susceptible strains, clinafloxacin tested alone was the most active treatment, decreasing the bacterial inoculum by more than 3 log10 CFU/ml after 24 h in time-kill curve studies.
AB - We evaluated the in vitro activities of clinafloxacin, CL331,002, LY333328, quinupristin dalfopristin, and eperezolid (formerly known as U- 100,592) against four strains of enterococci. All regimens tested resulted in the growth inhibition of each isolate. Against the three clinafloxacin- susceptible strains, clinafloxacin tested alone was the most active treatment, decreasing the bacterial inoculum by more than 3 log10 CFU/ml after 24 h in time-kill curve studies.
UR - http://www.scopus.com/inward/record.url?scp=0030671391&partnerID=8YFLogxK
U2 - 10.1128/aac.41.11.2573
DO - 10.1128/aac.41.11.2573
M3 - Article
C2 - 9371372
AN - SCOPUS:0030671391
SN - 0066-4804
VL - 41
SP - 2573
EP - 2575
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 11
ER -