Hormone-Related Migraine Headaches and Mood Disorders: Treatment with Estrogen Stabilization

Julia K. Warnock, Lawrence J. Cohen, Harvey Blumenthal, Jordan E. Hammond

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Because estrogens and the trigeminal system are inherently linked, prescribers who are treating a woman with a hormonally related mood disorder and migraine headaches should consider hormonal options to optimize the patient's treatment. This article discusses the interrelationships of estrogen, serotonin, and the trigeminal system as they relate to menstrual migraine occurrence and hormone-related mood symptoms. In addition, clinical examples are provided to facilitate the prescribers treating women during reproductive transitions in which declining estrogens are related to their suffering.

Original languageEnglish
Pages (from-to)120-128
Number of pages9
Issue number1
StatePublished - 1 Jan 2017


  • depression
  • estrogen
  • menstrual migraine


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