Hinf I/Tsp509 I and BsoF I polymorphisms in the flanking regions of the human VNTR locus D1S80

George T. Duncan, Kuppareddi Balamurugan, Bruce Budowle, Martin L. Tracey

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The minisatellite locus D1S80 (1p35-p36), is a highly polymorphic VNTR that also contains a Hinf I polymorphism in the 5' flanking region. Our data suggests that the Hinf I polymorphism is a G > T transversion 58 bases downstream from the forward primer. This G > T transversion also creates a Tsp509 I restriction site. Additionally, a G > C transversion polymorphism was identified in the 3' flanking region by the creation of a Bso F I restriction site immediately adjacent to the repeat region.

Original languageEnglish
Pages (from-to)119-121
Number of pages3
JournalGenetic Analysis - Biomolecular Engineering
Volume13
Issue number5
DOIs
StatePublished - 1 Nov 1996

Keywords

  • D1S80
  • Forensics
  • Minisatellite
  • Polymorphism
  • Sequence
  • Variable number tandem repeat (VNTR)

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