High-frequency phenotypic switching in Candida albicans

David R. Soll, Brian Morrow, Srikantha Thyagarajan

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Most strains of Candida albicans are capable of switching spontaneously and at high frequencies between a number of phenotypes distinguished by colony morphology. Unlike switching in many other microbial pathogens, switching in C. albicans is pleiotropic, affecting several morphological and physiological parameters. Recently, the first phase-specific genes were identified and shown to be regulated at the level of gene transcription.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalTrends in Genetics
Volume9
Issue number2
DOIs
StatePublished - 1 Jan 1993

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Candida albicans
Genes
Phenotype

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Soll, David R. ; Morrow, Brian ; Thyagarajan, Srikantha. / High-frequency phenotypic switching in Candida albicans. In: Trends in Genetics. 1993 ; Vol. 9, No. 2. pp. 61-65.
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High-frequency phenotypic switching in Candida albicans. / Soll, David R.; Morrow, Brian; Thyagarajan, Srikantha.

In: Trends in Genetics, Vol. 9, No. 2, 01.01.1993, p. 61-65.

Research output: Contribution to journalArticle

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