Gremlin induces ocular hypertension in mice through Smad3-dependent signaling

Keyphrases

• Ocular Hypertension 100%
• Smad3 100%
• Gremlin 100%
• Trabecular Meshwork 63%
• Immunofluorescence 18%
• Fibronectin 18%
• Glaucomatous 18%
• Extracellular Matrix Protein 1 (ECM1) 18%
• Collagen Type 1 18%
• Gene Expression 9%
• Trabecular Meshwork Cells 9%
• IOP Elevation 9%
• Wild Mice 9%
• Transforming Growth Factor-β 9%
• Quantitative PCR 9%
• In Vivo Model Systems 9%
• Elevated IOP 9%
• Tonometer 9%
• Surrounding Tissues 9%
• Bone Morphogenetic Protein 9%
• TonoLab 9%
• Intravitreal Injection 9%
• Western Blot Analysis 9%
• KO Mice 9%
• Western Immunoblotting 9%
• PCR Analysis 9%
• Profibrotic 9%
• Bone Morphogenetic Protein Antagonist 9%
• Perfusion Culture 9%
• Fibronectin 1 9%
• Intraocular Pressure Measurement 9%
• Ex Vivo Perfusion 9%
• Culture Model 9%
• Extracellular Matrix Remodeling 9%

Biochemistry, Genetics and Molecular Biology

• Fibronectin 100%
• Immunofluorescence 66%
• Bone Morphogenetic Protein 66%
• Wild Type Mouse 33%
• Intraocular Pressure 33%
• Extracellular Matrix Proteins 33%
• Scleroprotein 33%
• Knockout Mouse 33%
• Gene Expression 33%
• Perfusion 33%
• Real-Time Polymerase Chain Reaction 33%
• Extracellular Matrix Protein 33%
• Western Blotting 33%
• Cancer Growth Factor 33%
• Immunoblotting 33%

Neuroscience

• Ocular Hypertension 100%
• Trabecular Meshwork 100%
• Fibronectin 37%
• Collagen Type 1 25%
• Bone Morphogenetic Protein 25%
• Extracellular Matrix 25%
• Immunofluorescence 25%
• Intraocular Pressure 12%
• In Vivo 12%
• Gene Expression 12%
• Extracellular Matrix Proteins 12%
• Prothrombin 12%
• Matrix Protein 12%
• Real-Time Polymerase Chain Reaction 12%
• Western Blotting 12%
• Cancer Growth Factor 12%
• Immunoblotting 12%