Genetic variations at four tetrameric tandem repeat loci in Korean population

Su Jeong Park, Woo Ghil Lee, Seung Whan Lee, Sang Hae Kim, Bon Sung Koo, Bruce Budowle, Hyune Mo Rho

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.

Original languageEnglish
Pages (from-to)125-129
Number of pages5
JournalJournal of Forensic Sciences
Volume42
Issue number1
DOIs
StatePublished - Jan 1997

Keywords

  • CYAR04
  • DNA typing
  • FES/FPS
  • FOLP23
  • GABRB15
  • Hardy-Weinberg equilibrium
  • Korea
  • forensic science
  • population genetics
  • short tandem repeat

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