Genetic variations at four tetrameric tandem repeat loci in Korean population

Su Jeong Park; Woo Ghil Lee; Seung Whan Lee; Sang Hae Kim; Bon Sung Koo; Bruce Budowle; Hyune Mo Rho

doi:10.1520/jfs14081j

Genetic variations at four tetrameric tandem repeat loci in Korean population

Su Jeong Park, Woo Ghil Lee, Seung Whan Lee, Sang Hae Kim, Bon Sung Koo, Bruce Budowle, Hyune Mo Rho

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.

Original language	English
Pages (from-to)	125-129
Number of pages	5
Journal	Journal of Forensic Sciences
Volume	42
Issue number	1
DOIs	https://doi.org/10.1520/jfs14081j
State	Published - Jan 1997

Keywords

CYAR04
DNA typing
FES/FPS
FOLP23
GABRB15
Hardy-Weinberg equilibrium
Korea
forensic science
population genetics
short tandem repeat

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abstract = "Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.",

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AU - Park, Su Jeong

AU - Lee, Woo Ghil

AU - Lee, Seung Whan

AU - Kim, Sang Hae

AU - Koo, Bon Sung

AU - Budowle, Bruce

AU - Rho, Hyune Mo

PY - 1997/1

Y1 - 1997/1

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AB - Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.

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KW - DNA typing

KW - FES/FPS

KW - FOLP23

KW - GABRB15

KW - Hardy-Weinberg equilibrium

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KW - population genetics

KW - short tandem repeat

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Genetic variations at four tetrameric tandem repeat loci in Korean population

Abstract

Keywords

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