Genetic variation by birth cohorts in Mexican Americans of Starr County, Texas

Ricardo M. Cerda‐Flores, Sara A. Barton, Craig L. Hanis, Ranajit Chakraborty

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Mexican Americans residing in Starr County, Texas, were grouped by their year of birth (1896–1925, 1926–1955, and 1956–1985) to determine the extent of birth cohort‐related genetic variation within this population and the genetic differences, if any, from the Mexican population residing in the Metropolitan Monterrey Area (MMA), Nuevo León, México. Twenty‐one genetic markers were analyzed which indicate that the three birth cohort groups are genetically indistinguishable. Gene diversity analysis suggests that more than 99.8% of the total gene diversity can be attributed to variation between individuals within the birth cohort populations and that the subdivision by birth cohort has only a small contribution (0.18%) to the total gene diversity. Genetic admixture analysis indicates a predominant influence from the Spanish, and that the three birth cohort groups were similar in terms of contributions of this ancestral population. The genetic structure of the Mexican American population of Starr County was also similar to the Mexican population from the State of Nuevo León, México. These findings, together with previous results, suggest that the Mexican Americans of Starr County, Texas, classified by gender, birthplace, and age, are not genetically distinguishable and are similar to the Mexican populations of the State of Nuevo León. © 1994 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)669-674
Number of pages6
JournalAmerican Journal of Human Biology
Volume6
Issue number5
DOIs
StatePublished - 1994

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Mexican Americans
genetic variation
Parturition
gene
Population
individual variation
genetic marker
genetic analysis
genetic structure
metropolitan area
gender
Genes
Genetic Structures
Population Genetics
genes
Genetic Markers
genetic techniques and protocols
agglomeration area
Group
genetic markers

Cite this

Cerda‐Flores, Ricardo M. ; Barton, Sara A. ; Hanis, Craig L. ; Chakraborty, Ranajit. / Genetic variation by birth cohorts in Mexican Americans of Starr County, Texas. In: American Journal of Human Biology. 1994 ; Vol. 6, No. 5. pp. 669-674.
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abstract = "Mexican Americans residing in Starr County, Texas, were grouped by their year of birth (1896–1925, 1926–1955, and 1956–1985) to determine the extent of birth cohort‐related genetic variation within this population and the genetic differences, if any, from the Mexican population residing in the Metropolitan Monterrey Area (MMA), Nuevo Le{\'o}n, M{\'e}xico. Twenty‐one genetic markers were analyzed which indicate that the three birth cohort groups are genetically indistinguishable. Gene diversity analysis suggests that more than 99.8{\%} of the total gene diversity can be attributed to variation between individuals within the birth cohort populations and that the subdivision by birth cohort has only a small contribution (0.18{\%}) to the total gene diversity. Genetic admixture analysis indicates a predominant influence from the Spanish, and that the three birth cohort groups were similar in terms of contributions of this ancestral population. The genetic structure of the Mexican American population of Starr County was also similar to the Mexican population from the State of Nuevo Le{\'o}n, M{\'e}xico. These findings, together with previous results, suggest that the Mexican Americans of Starr County, Texas, classified by gender, birthplace, and age, are not genetically distinguishable and are similar to the Mexican populations of the State of Nuevo Le{\'o}n. {\circledC} 1994 Wiley‐Liss, Inc.",
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Genetic variation by birth cohorts in Mexican Americans of Starr County, Texas. / Cerda‐Flores, Ricardo M.; Barton, Sara A.; Hanis, Craig L.; Chakraborty, Ranajit.

In: American Journal of Human Biology, Vol. 6, No. 5, 1994, p. 669-674.

Research output: Contribution to journalArticle

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