TY - JOUR
T1 - Genetic study with autosomal STR markers in people of the Peruvian jungle for human identification purposes
AU - Carlos David, Neyra Rivera
AU - Edgardo, Delgado Ramos
AU - Fabiola, Díaz Soria
AU - José Santos, Quispe Ramírez
AU - Jianye, Ge
AU - Bruce, Budowle
N1 - Funding Information:
This work was supported by the Office of the Vice President for Research, Innovation and Entrepreneurship (Call for Research Projects UAP-2018) at the Universidad Alas Peruanas (Resolution No. 1C-006-VIeIT-2018). This project was evaluated by the Research Ethics Committee of the Alas Peruanas University, which approved this project and the use of human subjects by issuing a certificate of approval for one year (Approval document, CEI-006-2018). We especially thank to the National Institute of Health for the facilities and equipment for the research.
Publisher Copyright:
© 2021 Canadian Society of Forensic Science.
PY - 2021
Y1 - 2021
N2 - In the present study allele frequencies and other population parameters were determined for forensically-relevant Short Tandem Repeat (STR) markers in 278 Peruvians born and resident in the Peruvian jungle in total and separated into the subpopulations Amazonas, Loreto, and Madre de Dios. The samples were analyzed using the VeriFilerTM Express kit which enables typing of 23 STR loci and an amelogenin marker for sex determination. The parameters assessed and reported herein were allele frequencies, the power of discrimination (PD), departures from Hardy-Weinberg equilibrium, and estimates of the population distances. Under the assumption of independence, when comparing the population of the Peruvian jungle with a Peruvian mestizo population, Aymara population of Peru, Ashaninca of Peru, Hispanic Americans, and a Bolivia mestizo population, the largest genetic distance (Fst) was with the Hispanic population (Fst = 0.0343), and the smallest was with the Peruvian mestizo population (Fst = 0.0126). The jungle subpopulation showed greater distances in some comparisons. This study provides population data from a unique population residing in the Peruvian jungle which could be used to estimate various statistics of forensic interest for human identification.
AB - In the present study allele frequencies and other population parameters were determined for forensically-relevant Short Tandem Repeat (STR) markers in 278 Peruvians born and resident in the Peruvian jungle in total and separated into the subpopulations Amazonas, Loreto, and Madre de Dios. The samples were analyzed using the VeriFilerTM Express kit which enables typing of 23 STR loci and an amelogenin marker for sex determination. The parameters assessed and reported herein were allele frequencies, the power of discrimination (PD), departures from Hardy-Weinberg equilibrium, and estimates of the population distances. Under the assumption of independence, when comparing the population of the Peruvian jungle with a Peruvian mestizo population, Aymara population of Peru, Ashaninca of Peru, Hispanic Americans, and a Bolivia mestizo population, the largest genetic distance (Fst) was with the Hispanic population (Fst = 0.0343), and the smallest was with the Peruvian mestizo population (Fst = 0.0126). The jungle subpopulation showed greater distances in some comparisons. This study provides population data from a unique population residing in the Peruvian jungle which could be used to estimate various statistics of forensic interest for human identification.
KW - Allelic frequencies
KW - DNA
KW - STR marker
KW - genetic distance
KW - human identification
UR - http://www.scopus.com/inward/record.url?scp=85109302221&partnerID=8YFLogxK
U2 - 10.1080/00085030.2021.1933811
DO - 10.1080/00085030.2021.1933811
M3 - Article
AN - SCOPUS:85109302221
SN - 0008-5030
VL - 54
SP - 117
EP - 138
JO - Journal of the Canadian Society of Forensic Science
JF - Journal of the Canadian Society of Forensic Science
IS - 3
ER -