Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma

Hart B. Moss; Sai Chavala; Emil Say; Melissa B. Miller

doi:10.1128/JCM.00029-12

Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma

Hart B. Moss, Sai Chavala, Emil Say, Melissa B. Miller

North Texas Eye Research Institute

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A patient with systemic cytomegalovirus (CMV), including chorioretinitis, received localized and systemic ganciclovir, systemic cidofovir analog, and localized foscarnet. Mutations conferring ganciclovir and cidofovir resistance were detected in CMV from the aqueous fluid but not in CMV from plasma. Quantifying CMV from aqueous fluid was valuable for monitoring the clinical response and predicting resistance.

Original language	English
Pages (from-to)	1796-1799
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	50
Issue number	5
DOIs	https://doi.org/10.1128/JCM.00029-12
State	Published - May 2012

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abstract = "A patient with systemic cytomegalovirus (CMV), including chorioretinitis, received localized and systemic ganciclovir, systemic cidofovir analog, and localized foscarnet. Mutations conferring ganciclovir and cidofovir resistance were detected in CMV from the aqueous fluid but not in CMV from plasma. Quantifying CMV from aqueous fluid was valuable for monitoring the clinical response and predicting resistance.",

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AU - Say, Emil

AU - Miller, Melissa B.

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AB - A patient with systemic cytomegalovirus (CMV), including chorioretinitis, received localized and systemic ganciclovir, systemic cidofovir analog, and localized foscarnet. Mutations conferring ganciclovir and cidofovir resistance were detected in CMV from the aqueous fluid but not in CMV from plasma. Quantifying CMV from aqueous fluid was valuable for monitoring the clinical response and predicting resistance.

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Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma

Abstract

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