From the 90's to now: A brief historical perspective on more than two decades of estrogen neuroprotection

Keyphrases

• 17-estradiol 8%
• Activational Effects 8%
• Active Avoidance 16%
• Age-related 8%
• Age-related Illnesses 8%
• Alzheimer's Disease 16%
• Alzheimer's Disease Risk 8%
• Article Abstract 8%
• Beneficial Effects 8%
• Brain Disorders 8%
• Brain Substrates 8%
• Chemical Structure 8%
• Choline Acetyltransferase (ChAT) 41%
• Cholinergic Function 8%
• Cholinergic Neurons 8%
• Cholinergic System 8%
• Clinical Investigation 8%
• Cognitive Aging 8%
• Cognitive Benefits 8%
• Cognitive Deficits 8%
• Dementia 8%
• Deprivation 8%
• Disease-associated 8%
• Dysregulated 8%
• E2 Replacement 25%
• Estradiol 8%
• Estrogen 100%
• Estrogen Therapy 8%
• Estrogen Treatment 8%
• Estrogenic 8%
• Exogenous Estrogen 8%
• Frontal Cortex 33%
• Gonadal Hormones 8%
• High-affinity Choline Uptake 25%
• Hippocampus 25%
• Historical Perspective 100%
• Hormone Therapy 8%
• In Vitro Model 8%
• Intervention Development 8%
• Learning Impairment 8%
• Learning Memory 8%
• Learning Rate 8%
• Menopausal Hormone Therapy 8%
• Menopausal Symptoms 8%
• Morris Water Task 25%
• Neurochemical Analysis 8%
• Neuroprotection 100%
• Neuroprotective Action 16%
• Neuroprotective Effect 8%
• Organizational Effects 8%
• Ovarian Steroids 8%
• Ovariectomized 8%
• Ovariectomy 8%
• Pellet Groups 8%
• Physiological Level 8%
• Positive Control 8%
• Postmenopausal Women 8%
• Reproductive Tissues 8%
• Rodent Models 8%
• Sex Hormones 8%
• Sexual Behavior 8%
• Silastic 8%
• Sprague-Dawley Rats 16%
• Stroke Disease 8%
• Superior Performance 8%
• Task Affinity 8%
• Task Performance 8%
• Therapy Options 8%
• Treatment Group 8%
• Two-way Active Avoidance 8%

Neuroscience

• Active Avoidance 60%
• Alzheimer's Disease 60%
• Basal Forebrain 20%
• Behavior (Neuroscience) 20%
• Choline Acetyltransferase 100%
• Choline Uptake 60%
• Cholinergic 80%
• Cognitive Disorders 20%
• Diethylstilbestrol 40%
• Frontal Lobe 80%
• Hippocampus 60%
• Hormone Therapy 40%
• In Vitro 20%
• In Vivo 20%
• Learning Disabilities 20%
• Neuroprotection 100%
• Neuroprotective Agent 60%
• Sex Hormone 40%
• Sexual Behavior 20%