Abstract
Population studies on Caucasians from northwest Germany were carried out using the short tandem repeat (STR) systems SE 33 (Locus: ACTBP2) and TC 11 (Locus: 11p15.5). After electrophoresis in PAG 26 alleles could be identified for SE 33 in a sample size of 180 unrelated individuals and 6 alleles were found for TC 11 in 110 individuals. The combined mean exclusion chance for both systems was 0.96 and the discrimination index 0.999. No significant deviations from Hardy-Weinberg equilibrium could be demonstrated. In a small sample of families (SE 33 -n = 21; TC 11 -n = 30) no new mutations could be found. Positive and reproducible results for both STRs could be obtained from 50 pg template DNA.
Original language | English |
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Pages (from-to) | 315-320 |
Number of pages | 6 |
Journal | International Journal of Legal Medicine |
Volume | 105 |
Issue number | 6 |
DOIs | |
State | Published - 1 Nov 1993 |
Keywords
- Forensic validation
- Population studies
- SE 33
- Short tandem repeats
- TC 11