Fluvoxamine reduces the clozapine dosage needed in refractory schizophrenic patients

Keyphrases

• Add-on Therapy 6%
• Adverse Effects 6%
• Clinical Improvement 6%
• Clozapine 100%
• Clozapine-N-oxide 13%
• Combined Treatment 20%
• Cytochrome P450 1A2 (CYP1A2) 6%
• Day 14 6%
• Dosage Adjustment 6%
• Drug Combination 6%
• DSM-IV 6%
• Economic Impact 6%
• Fluvoxamine 100%
• Non-smokers 13%
• Norclozapine 20%
• Patient-completed 6%
• Patients with Schizophrenia 6%
• Plasma Parameters 13%
• Rating Instruments 6%
• Refractory Patients 13%
• Schizophrenia 6%
• Schizophrenic Patients 100%
• Smokers 20%
• Steady-state Conditions 6%
• Target Dose 6%
• Treatment Refractory 13%

Biochemistry, Genetics and Molecular Biology

• Blood Level 11%
• Blood Plasma 52%
• Clozapine 100%
• CYP1A2 5%
• Desmethylclozapine 17%
• DSM-IV 5%
• Fluvoxamine 100%
• Low Drug Dose 5%
• Pine 5%
• Prospective Study 5%
• Steady State 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Add on Therapy 6%
• Clozapine 100%
• Clozapine N Oxide 13%
• Combination Drug 6%
• CYP1A2 6%
• Desmethylclozapine 20%
• DSM-IV 6%
• Fluvoxamine 100%
• Pine 6%
• Prospective Study 6%
• Side Effect 13%