TY - JOUR
T1 - Fluorescence quenching/enhancement surface assays
T2 - Signal manipulation using silver-coated gold nanoparticles
AU - Matveeva, Evgenia G.
AU - Shtoyko, Tanya
AU - Gryczynski, Ignacy
AU - Akopova, Irina
AU - Gryczynski, Zygmunt
N1 - Funding Information:
This work was supported by Texas Emerging Technologies Fund Grant, NIH HG 004364, NSF (DBI-0649889), and Welch Foundation (BP-0037).
PY - 2008/3/10
Y1 - 2008/3/10
N2 - Gold nanoparticles covalently attached to the indium tin oxide coated glass slide drastically quench fluorescence of a surface immunoassay (approximately 5-fold). Silver electrochemically deposited over the gold particles leads to fluorescence amplification: signal increases approximately 7-8 times if compared to the signal on gold particles not covered with silver. This phenomenon allows enhancing of the surface immunoassays utilizing both types of nanoparticles.
AB - Gold nanoparticles covalently attached to the indium tin oxide coated glass slide drastically quench fluorescence of a surface immunoassay (approximately 5-fold). Silver electrochemically deposited over the gold particles leads to fluorescence amplification: signal increases approximately 7-8 times if compared to the signal on gold particles not covered with silver. This phenomenon allows enhancing of the surface immunoassays utilizing both types of nanoparticles.
UR - http://www.scopus.com/inward/record.url?scp=39749142545&partnerID=8YFLogxK
U2 - 10.1016/j.cplett.2008.01.075
DO - 10.1016/j.cplett.2008.01.075
M3 - Article
AN - SCOPUS:39749142545
SN - 0009-2614
VL - 454
SP - 85
EP - 90
JO - Chemical Physics Letters
JF - Chemical Physics Letters
IS - 1-3
ER -