Abstract
A fluorescence lifetime imaging probe with a long lifetime was used in combination with time-gating for the detection of hyaluronidase using hyaluronic acid as the probe template. This probe was developed by heavily labeling hyaluronic acid with long lifetime azadioxatriangulenium fluorophores (ADOTA). We used this probe to image hyaluronidase produced by DU-145 prostate cancer cells.
Original language | English |
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Pages (from-to) | 47001 |
Number of pages | 1 |
Journal | Methods and Applications in Fluorescence |
Volume | 4 |
Issue number | 4 |
DOIs | |
State | Published - 17 Nov 2016 |