Fluorescence detection: Gains in sensitivity

Chris D. Geddes, Ignacy Gryczynski, Joanna Malicka, Zygmunt Gryczynski, Joseph R. Lakowicz

Research output: Contribution to specialist publicationArticle

5 Scopus citations


The biotechnology and medical diagnostics industries could soon benefit from a technique that promises enhanced sensitivity over conventional fluorescence detection methods. As such, surface-plasmon-coupled emission shows promise to expand its chemical and biological sensing applications. Surface plasmons are basically electron oscillations on the surface of metals-or, more specifically, in an interfacial region between a metal and a dielectric medium. Although usually nonradiative, they are the basis of surface plasmon resonance.

Original languageEnglish
Specialist publicationPhotonics Spectra
StatePublished - Feb 2004


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