Fixed bin frequency distributions for the VNTR locus D5S110 in general United States reference databases

Bruce Budowle, A. M. Giusti

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations, and there is no evidence for association of alleles between the D5S110 and other routinely used VNTR loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in various general United States populations.

Original languageEnglish
Pages (from-to)236-238
Number of pages3
JournalJournal of Forensic Sciences
Volume40
Issue number2
StatePublished - 1 Jan 1995

Keywords

  • D5S110
  • RFLP
  • VNTR
  • allele frequency
  • equilibrium
  • forensic science
  • population databases

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