Fibulin-3 knockout mice demonstrate corneal dysfunction but maintain normal retinal integrity

Keyphrases

• Knock-in Mouse Model 100%
• Retinal Integrity 100%
• Fibulin-3 100%
• Retinal pigment Epithelium 44%
• Deposit Formation 16%
• Subretinal 16%
• Trabecular Meshwork 11%
• Optic Nerve 11%
• Cornea 11%
• Therapeutic Strategies 5%
• Human Patients 5%
• Histological Analysis 5%
• Mouse Eye 5%
• Spectral Domain Optical Coherence Tomography (SD-OCT) 5%
• Gain-of-function mutation 5%
• Autosomal Dominant 5%
• Age-related Macular Degeneration 5%
• Ocular Tissues 5%
• Anterograde Transport 5%
• Scotopic 5%
• Specific Pattern 5%
• Neural Retina 5%
• Basement Membrane 5%
• Expression Pattern 5%
• Corneal Stroma 5%
• Functional Characterization 5%
• Corneal Opacity 5%
• Structural Integrity 5%
• Corneal Vascularization 5%
• Retinal Abnormalities 5%
• Structural Functionality 5%
• Macular Dystrophy 5%
• Extracellular Matrix Glycoprotein 5%
• Structural Deformity 5%
• Optokinetic Response 5%
• Electron Microscopy 5%
• Biallelic 5%
• Structural Characterization 5%
• Structural Morphology 5%
• Electroretinogram 5%
• Eye Cornea 5%
• Fibulin 5%

Medicine and Dentistry

• Fibulin 100%
• Retinal Pigment Epithelium 42%
• Optic Nerve 10%
• Trabecular Meshwork 10%
• Disease 5%
• Dark Adaptation 5%
• Extracellular Matrix 5%
• Age Related Macular Degeneration 5%
• Axoplasmic Transport 5%
• Basement Membrane 5%
• Glycoprotein 5%
• Optical Coherence Tomography 5%
• Choroid 5%
• Loss of Function Mutation 5%
• Stroma of Cornea 5%
• Cornea Opacity 5%
• Electron Microscopy 5%
• Macular Degeneration 5%
• Autosomal Dominant Inheritance 5%
• Optokinetic Response 5%
• Corneal Neovascularization 5%

Neuroscience

• Fibulin 100%
• Retinal Pigment Epithelium 36%
• Cornea 15%
• Trabecular Meshwork 10%
• Optic Nerve 10%
• Extracellular Matrix 5%
• Age-Related Macular Degeneration 5%
• Axoplasmic Transport 5%
• Basement Membrane 5%
• Optokinetic Response 5%
• Loss of Function Mutation 5%
• Glycoprotein 5%
• Macular Dystrophy 5%
• Choroid 5%
• Electron Microscopy 5%
• Corneal Stroma 5%