Factors Governing Selectivity of Dopamine Receptor Binding Compounds for D2R and D3R Subtypes

Keyphrases

• Allosteric Binding 20%
• Binding Motif 10%
• Binding Pocket 10%
• Binding Selectivity 20%
• Bitopic 10%
• Closed Conformation 20%
• D2 Dopamine Receptor 100%
• D3 Dopamine Receptor 100%
• Dopamine D3 100%
• Dopamine Receptor 100%
• Extracellular Loop 10%
• High Affinity 10%
• Ligand Binding 20%
• Modes of Engagement 10%
• Molecular Dynamics Simulation 10%
• Open Conformation 20%
• Ordered Water 10%
• Orthosteric 10%
• Orthosteric Binding Site 10%
• Pharmaceutics 20%
• Receptor Binding 100%
• Receptor Subtypes 10%
• Transmembrane 10%
• Trifluoromethylphenylpiperazine (TFMPP) 10%

Neuroscience

• Binding Site 14%
• Dopamine Receptor 100%
• Dopamine Receptor D2 100%
• Dopamine Receptor D3 100%
• Ligand Binding 28%
• Receptor Binding 100%
• Receptor Subtype 100%

Biochemistry, Genetics and Molecular Biology

• Binding Site 12%
• Conformation 50%
• Dopamine Receptor 100%
• Dopamine Receptor D2 100%
• Dopamine Receptor D3 100%
• Dynamics 12%
• Eicosanoid Receptor 12%
• Ligand Binding 25%
• Receptor Binding 100%