Eyeing endothelins: A cellular perspective

Ganesh Prasanna; Santosh Narayan; Raghu Krishnamoorthy; Thomas Yorio

doi:10.1023/A:1026005418874

Eyeing endothelins

A cellular perspective

Ganesh Prasanna, Santosh Narayan, Raghu Krishnamoorthy, Thomas Yorio

Research output: Contribution to journal › Review article › Research › peer-review

45 Citations (Scopus)

Abstract

Endothelin is an endogenous vasoactive peptide that is considered among the most potent vasoconstrictor substances known. In addition to its vascular effects, endothelins and their receptors have been shown to be present in the eye and to have a number of ocular actions that may be important for ocular homeostasis, but, in excess can be a potential contributor to ocular neuropathy in glaucoma. The current review focuses on the cellular and molecular aspects of endothelins and its receptors in the eye with an emphasis on its relationship to ocular function and its potential role in the etiology of glaucoma pathophysiology.

Original language	English
Pages (from-to)	71-88
Number of pages	18
Journal	Molecular and Cellular Biochemistry
Volume	253
Issue number	1-2
DOIs	https://doi.org/10.1023/A:1026005418874
State	Published - 1 Nov 2003

Fingerprint

Endothelin Receptors

Endothelins

Vasoconstrictor Agents

Glaucoma

Peptides

Blood Vessels

Homeostasis

Keywords

Endothelin
ET receptors
ET signaling
Glaucoma

Cite this

Prasanna, G., Narayan, S., Krishnamoorthy, R., & Yorio, T. (2003). Eyeing endothelins: A cellular perspective. Molecular and Cellular Biochemistry, 253(1-2), 71-88. https://doi.org/10.1023/A:1026005418874

Prasanna, Ganesh ; Narayan, Santosh ; Krishnamoorthy, Raghu ; Yorio, Thomas. / Eyeing endothelins : A cellular perspective. In: Molecular and Cellular Biochemistry. 2003 ; Vol. 253, No. 1-2. pp. 71-88.

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Prasanna, G, Narayan, S, Krishnamoorthy, R & Yorio, T 2003, 'Eyeing endothelins: A cellular perspective', Molecular and Cellular Biochemistry, vol. 253, no. 1-2, pp. 71-88. https://doi.org/10.1023/A:1026005418874

Eyeing endothelins : A cellular perspective. / Prasanna, Ganesh; Narayan, Santosh; Krishnamoorthy, Raghu ; Yorio, Thomas.

In: Molecular and Cellular Biochemistry, Vol. 253, No. 1-2, 01.11.2003, p. 71-88.

Research output: Contribution to journal › Review article › Research › peer-review

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