TY - JOUR
T1 - Exercise training bradycardia
T2 - The role of autonomic balance
AU - Smith, Michael L.
AU - Hudson, Donna L.
AU - Graitzer, Howard M.
AU - Raven, Peter B.
PY - 1989/2
Y1 - 1989/2
N2 - We used an algebraic model of resting heart rate (HRr), HRr - mn (HRo), to compare resting parasympathetic (n) and sympathetic (m) influence, intrinsic heart rate (HRo), and resting autonomic balance (Abal) in ten endurance-trained (ET) and ten nontrained (NT) men. The values of m, n, and Abal were determined by selective pharmacological blockade with atropine and metoprolol. HRo was obtained during double blockade with atropine and metoprolol. HRo and HRr were significantly lower (P ≤ 0.04 and P ≤ 0.01, respectively) in the ET subjects (79.5 ± 2.8 beats-min−l and 54.7 ± 3.0 beats-min−1 respectively) when compared to the NT subjects (86.6 ± 2.5 beats-min1 and 70.2 ± 3.1 beats-min−1, respectively). Parasympathetic influence (n) was greater in the ET subjects (P ≤ 0.04), while sympathetic influence (m) was slightly (P ≤ 0.05) less in the ET subjects. Consequently, the value of Abal was significantly less in the ET subjects (P ≤ 0.02), indicating that resting parasympathetic predominance was significantly greater in the ET subjects. We concluded that the exercise training bradycardia, observed in this group of subjects, was due to both a lower HRO and an Abal, with an augmented parasympathetic dominance.
AB - We used an algebraic model of resting heart rate (HRr), HRr - mn (HRo), to compare resting parasympathetic (n) and sympathetic (m) influence, intrinsic heart rate (HRo), and resting autonomic balance (Abal) in ten endurance-trained (ET) and ten nontrained (NT) men. The values of m, n, and Abal were determined by selective pharmacological blockade with atropine and metoprolol. HRo was obtained during double blockade with atropine and metoprolol. HRo and HRr were significantly lower (P ≤ 0.04 and P ≤ 0.01, respectively) in the ET subjects (79.5 ± 2.8 beats-min−l and 54.7 ± 3.0 beats-min−1 respectively) when compared to the NT subjects (86.6 ± 2.5 beats-min1 and 70.2 ± 3.1 beats-min−1, respectively). Parasympathetic influence (n) was greater in the ET subjects (P ≤ 0.04), while sympathetic influence (m) was slightly (P ≤ 0.05) less in the ET subjects. Consequently, the value of Abal was significantly less in the ET subjects (P ≤ 0.02), indicating that resting parasympathetic predominance was significantly greater in the ET subjects. We concluded that the exercise training bradycardia, observed in this group of subjects, was due to both a lower HRO and an Abal, with an augmented parasympathetic dominance.
UR - http://www.scopus.com/inward/record.url?scp=0024590322&partnerID=8YFLogxK
U2 - 10.1249/00005768-198902000-00008
DO - 10.1249/00005768-198902000-00008
M3 - Article
C2 - 2927300
AN - SCOPUS:0024590322
SN - 0195-9131
VL - 21
SP - 40
EP - 44
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 1
ER -