Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians

Bruce Budowle, Linda B. Jankowski, Harry W. Corey, Nancy T. Swec, Sharon Freck-Tootell, Joseph A. Pino, Robyn Schwartz, Carol A. Kelley, Margaret L. Tarver

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, PGM, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.

Original languageEnglish
Pages (from-to)223-225
Number of pages3
JournalJournal of Forensic Sciences
Volume42
Issue number2
DOIs
StatePublished - Mar 1997

Keywords

  • Caucasian
  • D7S8
  • DNA
  • GYPA
  • Gc
  • HBGG
  • Hardy-Weinberg equilibrium
  • LDLR
  • erythrocyte acid phosphatase
  • esterase D
  • forensic science
  • genetic markers
  • linkage equilibrium
  • phosphoglucomutase 1
  • polymarker
  • polymerase chain reaction
  • population genetics

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    Budowle, B., Jankowski, L. B., Corey, H. W., Swec, N. T., Freck-Tootell, S., Pino, J. A., Schwartz, R., Kelley, C. A., & Tarver, M. L. (1997). Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians. Journal of Forensic Sciences, 42(2), 223-225. https://doi.org/10.1520/jfs14101j