Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians

Bruce Budowle; Linda B. Jankowski; Harry W. Corey; Nancy T. Swec; Sharon Freck-Tootell; Joseph A. Pino; Robyn Schwartz; Carol A. Kelley; Margaret L. Tarver

doi:10.1520/jfs14101j

Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians

Bruce Budowle, Linda B. Jankowski, Harry W. Corey, Nancy T. Swec, Sharon Freck-Tootell, Joseph A. Pino, Robyn Schwartz, Carol A. Kelley, Margaret L. Tarver

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, PGM, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.

Original language	English
Pages (from-to)	223-225
Number of pages	3
Journal	Journal of Forensic Sciences
Volume	42
Issue number	2
DOIs	https://doi.org/10.1520/jfs14101j
State	Published - Mar 1997

Keywords

Caucasian
D7S8
DNA
GYPA
Gc
HBGG
Hardy-Weinberg equilibrium
LDLR
erythrocyte acid phosphatase
esterase D
forensic science
genetic markers
linkage equilibrium
phosphoglucomutase 1
polymarker
polymerase chain reaction
population genetics

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10.1520/jfs14101j

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@article{eebb70bd99b6412fa12618c8b5c4288e,

title = "Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians",

abstract = "Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, PGM, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.",

keywords = "Caucasian, D7S8, DNA, GYPA, Gc, HBGG, Hardy-Weinberg equilibrium, LDLR, erythrocyte acid phosphatase, esterase D, forensic science, genetic markers, linkage equilibrium, phosphoglucomutase 1, polymarker, polymerase chain reaction, population genetics",

author = "Bruce Budowle and Jankowski, {Linda B.} and Corey, {Harry W.} and Swec, {Nancy T.} and Sharon Freck-Tootell and Pino, {Joseph A.} and Robyn Schwartz and Kelley, {Carol A.} and Tarver, {Margaret L.}",

year = "1997",

month = mar,

doi = "10.1520/jfs14101j",

language = "English",

volume = "42",

pages = "223--225",

journal = "Journal of forensic sciences",

issn = "0022-1198",

publisher = "Wiley-Blackwell",

number = "2",

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TY - JOUR

T1 - Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians

AU - Budowle, Bruce

AU - Jankowski, Linda B.

AU - Corey, Harry W.

AU - Swec, Nancy T.

AU - Freck-Tootell, Sharon

AU - Pino, Joseph A.

AU - Schwartz, Robyn

AU - Kelley, Carol A.

AU - Tarver, Margaret L.

PY - 1997/3

Y1 - 1997/3

N2 - Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, PGM, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.

AB - Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, PGM, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.

KW - Caucasian

KW - D7S8

KW - DNA

KW - GYPA

KW - Gc

KW - HBGG

KW - Hardy-Weinberg equilibrium

KW - LDLR

KW - erythrocyte acid phosphatase

KW - esterase D

KW - forensic science

KW - genetic markers

KW - linkage equilibrium

KW - phosphoglucomutase 1

KW - polymarker

KW - polymerase chain reaction

KW - population genetics

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DO - 10.1520/jfs14101j

M3 - Article

C2 - 9068180

AN - SCOPUS:0031054832

SN - 0022-1198

VL - 42

SP - 223

EP - 225

JO - Journal of forensic sciences

JF - Journal of forensic sciences

IS - 2

ER -

Evaluation of independence assumptions for PCR-based and protein-based genetic markers in New Jersey Caucasians

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Keywords

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