TY - JOUR
T1 - Enhanced fluorescence of curcumin on plasmonic platforms
AU - Mukerjee, Anindita
AU - Luchowski, Rafal
AU - Ranjan, Amalendu P.
AU - Raut, Sangram
AU - Vishwanatha, Jamboor K.
AU - Gryczynski, Zygmunt
AU - Gryczynski, Ignacy
PY - 2010/2
Y1 - 2010/2
N2 - We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3- methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.
AB - We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3- methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.
KW - Brightness
KW - Curcumin
KW - Fluorescence lifetime
KW - Metal enhanced fluorescence
KW - Photostability
KW - Plasmonic platforms
UR - http://www.scopus.com/inward/record.url?scp=77949877054&partnerID=8YFLogxK
U2 - 10.2174/138920110790909623
DO - 10.2174/138920110790909623
M3 - Review article
C2 - 20210735
AN - SCOPUS:77949877054
SN - 1389-2010
VL - 11
SP - 223
EP - 228
JO - Current Pharmaceutical Biotechnology
JF - Current Pharmaceutical Biotechnology
IS - 2
ER -