Enhanced fluorescence of curcumin on plasmonic platforms

Anindita Mukerjee, Rafal Luchowski, Amalendu Prakash Ranjan, Sangram Limbaji Raut, Jamboor K. Vishwanatha, Zygmunt Gryczynski, Ignacy Gryczynski

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3- methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.

Original languageEnglish
Pages (from-to)223-228
Number of pages6
JournalCurrent Pharmaceutical Biotechnology
Volume11
Issue number2
DOIs
StatePublished - 1 Feb 2010

Keywords

  • Brightness
  • Curcumin
  • Fluorescence lifetime
  • Metal enhanced fluorescence
  • Photostability
  • Plasmonic platforms

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