Electrophoretically silent alleles in a finite population

Masatoshi Nei; Ranajit Chakraborty

doi:10.1007/BF01739262

Electrophoretically silent alleles in a finite population

Masatoshi Nei, Ranajit Chakraborty

School of Biomedical Sciences

Research output: Contribution to journal › Letter › peer-review

Abstract

The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.

Original language	English
Pages (from-to)	381-385
Number of pages	5
Journal	Journal of Molecular Evolution
Volume	8
Issue number	4
DOIs	https://doi.org/10.1007/BF01739262
State	Published - Dec 1976

Keywords

Electrophoresis
Protein Polymorphism

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10.1007/BF01739262

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abstract = "The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.",

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author = "Masatoshi Nei and Ranajit Chakraborty",

year = "1976",

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AU - Nei, Masatoshi

AU - Chakraborty, Ranajit

PY - 1976/12

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N2 - The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.

AB - The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.

KW - Electrophoresis

KW - Protein Polymorphism

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U2 - 10.1007/BF01739262

DO - 10.1007/BF01739262

M3 - Letter

C2 - 1011266

AN - SCOPUS:0017319129

SN - 0022-2844

VL - 8

SP - 381

EP - 385

JO - Journal of Molecular Evolution

JF - Journal of Molecular Evolution

IS - 4

ER -

Electrophoretically silent alleles in a finite population

Abstract

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