Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

Michael W. Dunne; Chandra Khurana; Adriano Arguedas Mohs; Adib Rodriguez; Antonio Arrieta; Samuel McLinn; Judy A. Krogstad; Mark Blatter; Richard Schwartz; Sergio L. Vargas; Paz Emparanza; Pilar Fernandez; Willis M. Gooch; Mary Aspin; John Podgore; Irmeli Roine; Jeffrey L. Blumer; Garth D. Ehrlich; Jean Chow

doi:10.1128/AAC.47.8.2663-2665.2003

Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

Michael W. Dunne, Chandra Khurana, Adriano Arguedas Mohs, Adib Rodriguez, Antonio Arrieta, Samuel McLinn, Judy A. Krogstad, Mark Blatter, Richard Schwartz, Sergio L. Vargas, Paz Emparanza, Pilar Fernandez, Willis M. Gooch, Mary Aspin, John Podgore, Irmeli Roine, Jeffrey L. Blumer, Garth D. Ehrlich, Jean Chow

Pediatrics

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

Original language	English
Pages (from-to)	2663-2665
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	47
Issue number	8
DOIs	https://doi.org/10.1128/AAC.47.8.2663-2665.2003
State	Published - 1 Aug 2003

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Dunne, M. W., Khurana, C., Mohs, A. A., Rodriguez, A., Arrieta, A., McLinn, S., Krogstad, J. A., Blatter, M., Schwartz, R., Vargas, S. L., Emparanza, P., Fernandez, P., Gooch, W. M., Aspin, M., Podgore, J., Roine, I., Blumer, J. L., Ehrlich, G. D., & Chow, J. (2003). Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis. Antimicrobial agents and chemotherapy, 47(8), 2663-2665. https://doi.org/10.1128/AAC.47.8.2663-2665.2003

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title = "Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis",

abstract = "Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.",

author = "Dunne, {Michael W.} and Chandra Khurana and Mohs, {Adriano Arguedas} and Adib Rodriguez and Antonio Arrieta and Samuel McLinn and Krogstad, {Judy A.} and Mark Blatter and Richard Schwartz and Vargas, {Sergio L.} and Paz Emparanza and Pilar Fernandez and Gooch, {Willis M.} and Mary Aspin and John Podgore and Irmeli Roine and Blumer, {Jeffrey L.} and Ehrlich, {Garth D.} and Jean Chow",

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doi = "10.1128/AAC.47.8.2663-2665.2003",

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Dunne, MW, Khurana, C, Mohs, AA, Rodriguez, A, Arrieta, A, McLinn, S, Krogstad, JA, Blatter, M, Schwartz, R, Vargas, SL, Emparanza, P, Fernandez, P, Gooch, WM, Aspin, M, Podgore, J, Roine, I, Blumer, JL, Ehrlich, GD & Chow, J 2003, 'Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis', Antimicrobial agents and chemotherapy, vol. 47, no. 8, pp. 2663-2665. https://doi.org/10.1128/AAC.47.8.2663-2665.2003

TY - JOUR

T1 - Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

AU - Dunne, Michael W.

AU - Khurana, Chandra

AU - Mohs, Adriano Arguedas

AU - Rodriguez, Adib

AU - Arrieta, Antonio

AU - McLinn, Samuel

AU - Krogstad, Judy A.

AU - Blatter, Mark

AU - Schwartz, Richard

AU - Vargas, Sergio L.

AU - Emparanza, Paz

AU - Fernandez, Pilar

AU - Gooch, Willis M.

AU - Aspin, Mary

AU - Podgore, John

AU - Roine, Irmeli

AU - Blumer, Jeffrey L.

AU - Ehrlich, Garth D.

AU - Chow, Jean

PY - 2003/8/1

Y1 - 2003/8/1

N2 - Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

AB - Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

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U2 - 10.1128/AAC.47.8.2663-2665.2003

DO - 10.1128/AAC.47.8.2663-2665.2003

M3 - Article

C2 - 12878537

AN - SCOPUS:0042267996

SN - 0066-4804

VL - 47

SP - 2663

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JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

ER -

Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

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