Effects of schedules of reinforcement on brain catecholamine metabolism in the rat

L. H. Albert, Michael Oglesby, L. S. Seiden

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Rats were trained on a fixed ratio 5 (FR 5) for 0.01 ml water reinforcer, a fixed ratio 20 (FR 20) fir 0.01 ml water reinforcer, a fixed ratio 20 (FR 20) for 0.04 ml water reinforcer, a variable time 15 sec (VT 15 sec) for 0.01 ml water reinforcer, a variable time 30 sec (VT 30 sec) for 0.01 ml water, variable time 60 sec (VT 60 sec) for 0.01 ml water, or a variable time 60 sec (VT 60 sec) for 0.10 ml water. In all these schedules, the rate of NE metabolism varied with the number of water presentations but not with the number of responses or the volume of water. The rate of metabolism of DA was increased over control values in rats on the VT schedules but no significant differences could be found in DA metabolism among the rats performing on the various VT schedules or receiving various volumes.

Original languageEnglish
Pages (from-to)481-486
Number of pages6
JournalPharmacology, Biochemistry and Behavior
Volume6
Issue number5
DOIs
StatePublished - 1 Jan 1977

Fingerprint

Reinforcement Schedule
Metabolism
Catecholamines
Rats
Brain
Reinforcement
Water
Appointments and Schedules

Keywords

  • Brain catecholamine metabolism
  • Nonadrenergic neuronal activity
  • Schedules of reinforcement
  • Tyrosine-hydroxylase inhibitor
  • α-Methyl-p-tyrosine

Cite this

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Effects of schedules of reinforcement on brain catecholamine metabolism in the rat. / Albert, L. H.; Oglesby, Michael; Seiden, L. S.

In: Pharmacology, Biochemistry and Behavior, Vol. 6, No. 5, 01.01.1977, p. 481-486.

Research output: Contribution to journalArticle

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