Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Biochemistry, Genetics and Molecular Biology

• Genome-Wide Association Study 100%
• Genetic Disorder 100%
• PICALM 100%
• BIN1 100%
• Gene Locus 100%
• Single-Nucleotide Polymorphism 50%
• Allele 50%
• Genotyping 50%
• Genetics 50%
• Medical Record 50%

Keyphrases

• Genome-wide Association Study 100%
• Late-onset Alzheimer's Disease 100%
• Age of Onset 100%
• Multiple Genetic Loci 100%
• Risk Loci 22%
• Alzheimer's Disease Risk 16%
• Genetics of Alzheimer's Disease 11%
• BIN1 11%
• PICALM 11%
• Burden Analysis 11%
• Aggregate Effect 11%
• Single nucleotide Polymorphism 5%
• Family-centered 5%
• Alzheimer's Disease 5%
• Genetic Contribution 5%
• Medical Records 5%
• Race-ethnicity 5%
• Risk Allele 5%
• Risk Variant 5%
• Inverse-variance Weights 5%
• Random Effects 5%
• Statistical Significance 5%
• Meta-analysis Approach 5%
• Linear Modeling 5%
• Genotype Score 5%
• Hypothetical Modelling 5%
• Weighted Meta-analysis 5%
• Risk Effects 5%
• Cumulative Effects 5%
• White Race 5%
• Multiple Sites 5%