[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].

L. Liu; Hong Hui Zhang; Guo Xian Ding; Yun Lin Cheng; Liang Jun Yan; I. J. Benjamin

[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].

L. Liu, Hong Hui Zhang, Guo Xian Ding, Yun Lin Cheng, Liang Jun Yan, I. J. Benjamin

Research output: Contribution to journal › Article › peer-review

Abstract

Try to clarify the effects of HSF1 gene on the constitutively expressed alphaBC. To investigate the levels of constitutively expressed alphaB-Crystallin (alphaBC) in hsf1 knockout (hsf1 -/-) and hsf1 wild type (hsf1 +/+) mice myocardium by Western blot and immunohistochemistry. The alphaBC levels in hsf1 -/- and hsf1 +/+ were 68.42% +/- 4.16%, 100% +/- 7.58%, respectively (P < 0.05, cytosolic fraction), and 20.53% +/- 1.01%, 37.55% +/- 1.91%, respectively (P < 0.05, pellet fraction). The alphaBC signals decreased significantly in hsf1 -/- myocardium compared with hsf1 +/+ myocardium stained with fluorescence immunohistochemistry. hsf1 is the important, but not the only factor, which mediates the constitutively expressed alphaBC.

Original language	English
Pages (from-to)	30-33
Number of pages	4
Journal	Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
Volume	20
Issue number	1
State	Published - Feb 2004

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title = "[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].",

abstract = "Try to clarify the effects of HSF1 gene on the constitutively expressed alphaBC. To investigate the levels of constitutively expressed alphaB-Crystallin (alphaBC) in hsf1 knockout (hsf1 -/-) and hsf1 wild type (hsf1 +/+) mice myocardium by Western blot and immunohistochemistry. The alphaBC levels in hsf1 -/- and hsf1 +/+ were 68.42% +/- 4.16%, 100% +/- 7.58%, respectively (P < 0.05, cytosolic fraction), and 20.53% +/- 1.01%, 37.55% +/- 1.91%, respectively (P < 0.05, pellet fraction). The alphaBC signals decreased significantly in hsf1 -/- myocardium compared with hsf1 +/+ myocardium stained with fluorescence immunohistochemistry. hsf1 is the important, but not the only factor, which mediates the constitutively expressed alphaBC.",

author = "L. Liu and Zhang, {Hong Hui} and Ding, {Guo Xian} and Cheng, {Yun Lin} and Yan, {Liang Jun} and Benjamin, {I. J.}",

year = "2004",

month = feb,

language = "English",

volume = "20",

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journal = "Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology",

issn = "1000-6834",

publisher = "Zhongguo Yingyong Shenglixue Zazhi Bianjibu",

number = "1",

}

[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium]. / Liu, L.; Zhang, Hong Hui; Ding, Guo Xian et al.
In: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, Vol. 20, No. 1, 02.2004, p. 30-33.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - [Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].

AU - Liu, L.

AU - Zhang, Hong Hui

AU - Ding, Guo Xian

AU - Cheng, Yun Lin

AU - Yan, Liang Jun

AU - Benjamin, I. J.

PY - 2004/2

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N2 - Try to clarify the effects of HSF1 gene on the constitutively expressed alphaBC. To investigate the levels of constitutively expressed alphaB-Crystallin (alphaBC) in hsf1 knockout (hsf1 -/-) and hsf1 wild type (hsf1 +/+) mice myocardium by Western blot and immunohistochemistry. The alphaBC levels in hsf1 -/- and hsf1 +/+ were 68.42% +/- 4.16%, 100% +/- 7.58%, respectively (P < 0.05, cytosolic fraction), and 20.53% +/- 1.01%, 37.55% +/- 1.91%, respectively (P < 0.05, pellet fraction). The alphaBC signals decreased significantly in hsf1 -/- myocardium compared with hsf1 +/+ myocardium stained with fluorescence immunohistochemistry. hsf1 is the important, but not the only factor, which mediates the constitutively expressed alphaBC.

AB - Try to clarify the effects of HSF1 gene on the constitutively expressed alphaBC. To investigate the levels of constitutively expressed alphaB-Crystallin (alphaBC) in hsf1 knockout (hsf1 -/-) and hsf1 wild type (hsf1 +/+) mice myocardium by Western blot and immunohistochemistry. The alphaBC levels in hsf1 -/- and hsf1 +/+ were 68.42% +/- 4.16%, 100% +/- 7.58%, respectively (P < 0.05, cytosolic fraction), and 20.53% +/- 1.01%, 37.55% +/- 1.91%, respectively (P < 0.05, pellet fraction). The alphaBC signals decreased significantly in hsf1 -/- myocardium compared with hsf1 +/+ myocardium stained with fluorescence immunohistochemistry. hsf1 is the important, but not the only factor, which mediates the constitutively expressed alphaBC.

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C2 - 21162300

AN - SCOPUS:84871946560

SN - 1000-6834

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JO - Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology

JF - Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology

IS - 1

ER -

[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].

Abstract

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