Effects of carbamazepine on plasma haloperidol levels

Michael Wong Jann, Larry Ereshefsky, Stephen R. Saklad, Donald R. Seidel, Chester M. Davis, Neil R. Burch, Charles L. Bowden

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

Original languageEnglish
Pages (from-to)106-109
Number of pages4
JournalJournal of Clinical Psychopharmacology
Volume5
Issue number2
DOIs
StatePublished - 1 Jan 1985

Fingerprint

Carbamazepine
Haloperidol
Therapeutics

Cite this

Jann, M. W., Ereshefsky, L., Saklad, S. R., Seidel, D. R., Davis, C. M., Burch, N. R., & Bowden, C. L. (1985). Effects of carbamazepine on plasma haloperidol levels. Journal of Clinical Psychopharmacology, 5(2), 106-109. https://doi.org/10.1097/00004714-198504000-00010
Jann, Michael Wong ; Ereshefsky, Larry ; Saklad, Stephen R. ; Seidel, Donald R. ; Davis, Chester M. ; Burch, Neil R. ; Bowden, Charles L. / Effects of carbamazepine on plasma haloperidol levels. In: Journal of Clinical Psychopharmacology. 1985 ; Vol. 5, No. 2. pp. 106-109.
@article{ffa64272cfe049bd9196b24b66ee5ac6,
title = "Effects of carbamazepine on plasma haloperidol levels",
abstract = "Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59{\%} and 61{\%}. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.",
author = "Jann, {Michael Wong} and Larry Ereshefsky and Saklad, {Stephen R.} and Seidel, {Donald R.} and Davis, {Chester M.} and Burch, {Neil R.} and Bowden, {Charles L.}",
year = "1985",
month = "1",
day = "1",
doi = "10.1097/00004714-198504000-00010",
language = "English",
volume = "5",
pages = "106--109",
journal = "Journal of Clinical Psychopharmacology",
issn = "0271-0749",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "2",

}

Jann, MW, Ereshefsky, L, Saklad, SR, Seidel, DR, Davis, CM, Burch, NR & Bowden, CL 1985, 'Effects of carbamazepine on plasma haloperidol levels', Journal of Clinical Psychopharmacology, vol. 5, no. 2, pp. 106-109. https://doi.org/10.1097/00004714-198504000-00010

Effects of carbamazepine on plasma haloperidol levels. / Jann, Michael Wong; Ereshefsky, Larry; Saklad, Stephen R.; Seidel, Donald R.; Davis, Chester M.; Burch, Neil R.; Bowden, Charles L.

In: Journal of Clinical Psychopharmacology, Vol. 5, No. 2, 01.01.1985, p. 106-109.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effects of carbamazepine on plasma haloperidol levels

AU - Jann, Michael Wong

AU - Ereshefsky, Larry

AU - Saklad, Stephen R.

AU - Seidel, Donald R.

AU - Davis, Chester M.

AU - Burch, Neil R.

AU - Bowden, Charles L.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

AB - Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

UR - http://www.scopus.com/inward/record.url?scp=0021950571&partnerID=8YFLogxK

U2 - 10.1097/00004714-198504000-00010

DO - 10.1097/00004714-198504000-00010

M3 - Article

C2 - 3988968

AN - SCOPUS:0021950571

VL - 5

SP - 106

EP - 109

JO - Journal of Clinical Psychopharmacology

JF - Journal of Clinical Psychopharmacology

SN - 0271-0749

IS - 2

ER -