Effect of prenatal alcohol exposure on growth and morphology of offspring at 8 months of age

N. L. Day, G. Richardson, N. Robles, U. Sambamoorthi, P. Taylor, M. Scher, D. Stoffer, D. Jasperse, M. Cornelius

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

In this prospective study of alcohol and other substance use during pregnancy, a cohort of women was interviewed at each trimester of pregnancy and when the offspring were 8 months of age. Data are presented concerning the outcome for 461 infants. A significant relationship was found between alcohol use during pregnancy and the growth and morphology of the offspring at the 8-month follow-up observation. Alcohol use during the second and third trimesters of pregnancy and continuous use of alcohol throughout pregnancy were significantly related to lower weight, length, and head circumference in the exposed infants at the follow-up observation. A significant increase in the risk of minor physical anomalies and fetal alcohol effects was also predicted by prenatal alcohol exposure.

Original languageEnglish
Pages (from-to)748-752
Number of pages5
JournalPediatrics
Volume85
Issue number5
StatePublished - 1990

Keywords

  • Alcohol
  • Growth
  • Morphology
  • Pregnancy
  • Substance use

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