Effect of 60-minute head-down tilt on arterial baroreflex function in anesthetized dogs

Michael L. Smith; William G. Squires; Tedd A. Brandon; Peter B. Raven; Sarah A. Nunneley

doi:10.1016/0165-1838(87)90084-1

Effect of 60-minute head-down tilt on arterial baroreflex function in anesthetized dogs

Michael L. Smith, William G. Squires, Tedd A. Brandon, Peter B. Raven, Sarah A. Nunneley

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Arterial baroreflex control of heart rate was assessed in 6 anesthetized dogs with a bolus infusion of phenylephrine before and during cardiopulmonary receptor stimulation by 6° head-down tilt (HDT) for 60 min. No difference in arterial baroreflex function was observed between the control and HDT conditions. It appears that the attenuation of baroreflex function that occurs during acute stimulation of cardiopulmonary baroreceptors disappears when cardiopulmonary baroreceptors reset after prolonged stimulation.

Original language	English
Pages (from-to)	87-90
Number of pages	4
Journal	Journal of the Autonomic Nervous System
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/0165-1838(87)90084-1
State	Published - Jul 1987

Keywords

Arterial baroreceptor
Blood pressure
Cardiopulmonary baroreceptor
Dog
Phenylephrine
Resetting

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10.1016/0165-1838(87)90084-1

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title = "Effect of 60-minute head-down tilt on arterial baroreflex function in anesthetized dogs",

abstract = "Arterial baroreflex control of heart rate was assessed in 6 anesthetized dogs with a bolus infusion of phenylephrine before and during cardiopulmonary receptor stimulation by 6° head-down tilt (HDT) for 60 min. No difference in arterial baroreflex function was observed between the control and HDT conditions. It appears that the attenuation of baroreflex function that occurs during acute stimulation of cardiopulmonary baroreceptors disappears when cardiopulmonary baroreceptors reset after prolonged stimulation.",

keywords = "Arterial baroreceptor, Blood pressure, Cardiopulmonary baroreceptor, Dog, Phenylephrine, Resetting",

author = "Smith, {Michael L.} and Squires, {William G.} and Brandon, {Tedd A.} and Raven, {Peter B.} and Nunneley, {Sarah A.}",

note = "Funding Information: The authors wish to thank James Eldridge, Jeff Glover, and Michael Perry for their technical assistance. This research was supported in part by U.S.A. Department of the Air Force, contract no. F33615-83-D-0602-0018.",

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AU - Squires, William G.

AU - Brandon, Tedd A.

AU - Raven, Peter B.

AU - Nunneley, Sarah A.

N1 - Funding Information: The authors wish to thank James Eldridge, Jeff Glover, and Michael Perry for their technical assistance. This research was supported in part by U.S.A. Department of the Air Force, contract no. F33615-83-D-0602-0018.

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N2 - Arterial baroreflex control of heart rate was assessed in 6 anesthetized dogs with a bolus infusion of phenylephrine before and during cardiopulmonary receptor stimulation by 6° head-down tilt (HDT) for 60 min. No difference in arterial baroreflex function was observed between the control and HDT conditions. It appears that the attenuation of baroreflex function that occurs during acute stimulation of cardiopulmonary baroreceptors disappears when cardiopulmonary baroreceptors reset after prolonged stimulation.

AB - Arterial baroreflex control of heart rate was assessed in 6 anesthetized dogs with a bolus infusion of phenylephrine before and during cardiopulmonary receptor stimulation by 6° head-down tilt (HDT) for 60 min. No difference in arterial baroreflex function was observed between the control and HDT conditions. It appears that the attenuation of baroreflex function that occurs during acute stimulation of cardiopulmonary baroreceptors disappears when cardiopulmonary baroreceptors reset after prolonged stimulation.

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KW - Blood pressure

KW - Cardiopulmonary baroreceptor

KW - Dog

KW - Phenylephrine

KW - Resetting

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Effect of 60-minute head-down tilt on arterial baroreflex function in anesthetized dogs

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