Drug identification problems in two suicides with neuromuscular blocking agents

G. Somogyi; M. Varga; Laszlo Prokai; Z. Dinya; L. Buris

doi:10.1016/0379-0738(89)90153-9

Drug identification problems in two suicides with neuromuscular blocking agents

G. Somogyi, M. Varga, Laszlo Prokai, Z. Dinya, L. Buris

Institute for Healthy Aging

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6 Scopus citations

Abstract

Cases of suicide committed with neuromuscular blocking agents have been investigated. Both cases involved anesthesiologists who took the muscle relaxants suxamethonium chloride (Sukolin^r) or pipecuronium bromide (Arduan^r) and a rapid-acting barbiturate, 5-sec-butyl-5-ethyl-2-thiobarbituric acid (Inactin^r). The examinations were performed by using gas chromatography and mass spectrometry. The quantitative data obtained showed that doses useful in general anesthesiological practice were applied. Metabolites were found despite their fast metabolizing character.

Original language	English
Pages (from-to)	257-266
Number of pages	10
Journal	Forensic Science International
Volume	43
Issue number	3
DOIs	https://doi.org/10.1016/0379-0738(89)90153-9
State	Published - 1 Jan 1989

Keywords

Detection of muscle relaxants
Suicides committed with muscle relaxants

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abstract = "Cases of suicide committed with neuromuscular blocking agents have been investigated. Both cases involved anesthesiologists who took the muscle relaxants suxamethonium chloride (Sukolinr) or pipecuronium bromide (Arduanr) and a rapid-acting barbiturate, 5-sec-butyl-5-ethyl-2-thiobarbituric acid (Inactinr). The examinations were performed by using gas chromatography and mass spectrometry. The quantitative data obtained showed that doses useful in general anesthesiological practice were applied. Metabolites were found despite their fast metabolizing character.",

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AU - Somogyi, G.

AU - Varga, M.

AU - Prokai, Laszlo

AU - Dinya, Z.

AU - Buris, L.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - Cases of suicide committed with neuromuscular blocking agents have been investigated. Both cases involved anesthesiologists who took the muscle relaxants suxamethonium chloride (Sukolinr) or pipecuronium bromide (Arduanr) and a rapid-acting barbiturate, 5-sec-butyl-5-ethyl-2-thiobarbituric acid (Inactinr). The examinations were performed by using gas chromatography and mass spectrometry. The quantitative data obtained showed that doses useful in general anesthesiological practice were applied. Metabolites were found despite their fast metabolizing character.

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KW - Suicides committed with muscle relaxants

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Drug identification problems in two suicides with neuromuscular blocking agents

Abstract

Keywords

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