Distribution of types for six PCR-based loci; LDLR, GYPA, HBGG, D7S8, GC and HLA-DQA1 in central pyrenees and teruel (Spain)

Bianca Bell, Bruce Budowle, Begoña Martinez-Jarreta, Yolanda Casalod, Emilio Abecia, Maria Castellano

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The PCR-based DNA loci LDLR, GYPA, HBGG, D7S8, GC and HLA DQA1 are widely used in forensic casework analyses. Population data on the distribution of allele frequencies are desired to estimate the rarity of a DNA profile. We studied the allele distributions at these forensically important DNA markers in two Spanish populations (Central Pyrenees and Teruel). Results were in agreement with Hardy-Weinberg expectations. Furthermore, there was little evidence for departures from expectation of independence between loci within the two sample populations. Tests for homogeneity were carried out between the two Spanish populations and a U.S. Caucasian population.

Original languageEnglish
Pages (from-to)510-513
Number of pages4
JournalJournal of Forensic Sciences
Volume42
Issue number3
DOIs
StatePublished - May 1997

Keywords

  • Central Pyrenees
  • D7S8
  • DNA typing
  • GC
  • GYPA
  • HBGG
  • HLA-DQA1
  • LDLR
  • Spain
  • Teruel
  • forensic science
  • population genetics

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