Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates

Mohammad A. Tahir; Abdul Qader Al Khayat; Farida Al Shamali; Bruce Budowle; Gabriel E. Novick

doi:10.1016/S0379-0738(97)02103-8

Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates

Mohammad A. Tahir, Abdul Qader Al Khayat, Farida Al Shamali, Bruce Budowle, Gabriel E. Novick

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.

Original language	English
Pages (from-to)	219-223
Number of pages	5
Journal	Forensic Science International
Volume	85
Issue number	3
DOIs	https://doi.org/10.1016/S0379-0738(97)02103-8
State	Published - 14 Mar 1997

Keywords

Allelic frequencies
Arab
Forensic sciences
HLA-DQA1
PCR typing
Pakistani
Population genetics

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10.1016/S0379-0738(97)02103-8

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title = "Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates",

abstract = "PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.",

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T1 - Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates

AU - Tahir, Mohammad A.

AU - Qader Al Khayat, Abdul

AU - Al Shamali, Farida

AU - Budowle, Bruce

AU - Novick, Gabriel E.

PY - 1997/3/14

Y1 - 1997/3/14

N2 - PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.

AB - PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.

KW - Allelic frequencies

KW - Arab

KW - Forensic sciences

KW - HLA-DQA1

KW - PCR typing

KW - Pakistani

KW - Population genetics

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AN - SCOPUS:0031567145

SN - 0379-0738

VL - 85

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EP - 223

JO - Forensic Science International

JF - Forensic Science International

IS - 3

ER -

Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates

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Keywords

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