Distribution of HLA-DQA1 alleles in Arab and Pakistani individuals from Dubai, United Arab Emirates

Mohammad A. Tahir, Abdul Qader Al Khayat, Farida Al Shamali, Bruce Budowle, Gabriel E. Novick

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalForensic Science International
Volume85
Issue number3
DOIs
StatePublished - 14 Mar 1997

Keywords

  • Allelic frequencies
  • Arab
  • Forensic sciences
  • HLA-DQA1
  • PCR typing
  • Pakistani
  • Population genetics

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