Abstract
PCR-based typing of the HLA-DQA1 locus, using allele specific oligonucleotide (ASO) probes and reverse dot blot methodology was used to determine allelic distributions and construct a database for Arab and Pakistani individuals living in Dubai. Genotype and allelic frequencies were calculated, and the data were tested for departures from Hardy-Weinberg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubaian Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allele is also DQA1 4. No significant deviations from HWE were detected.
Original language | English |
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Pages (from-to) | 219-223 |
Number of pages | 5 |
Journal | Forensic Science International |
Volume | 85 |
Issue number | 3 |
DOIs | |
State | Published - 14 Mar 1997 |
Keywords
- Allelic frequencies
- Arab
- Forensic sciences
- HLA-DQA1
- PCR typing
- Pakistani
- Population genetics