Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates

Mohammad A. Tahir; Joseph Caruso; Bruce Budowle; Nasir Aziz; Gabriel E. Novick

doi:10.1520/jfs14230j

Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates

Mohammad A. Tahir, Joseph Caruso, Bruce Budowle, Nasir Aziz, Gabriel E. Novick

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.

Original language	English
Pages (from-to)	914-918
Number of pages	5
Journal	Journal of Forensic Sciences
Volume	42
Issue number	5
DOIs	https://doi.org/10.1520/jfs14230j
State	Published - Sep 1997

Keywords

Allele frequencies
Arab
D7S8
DNA typing
Forensic science
GC
GYPA
HBGG
HLA- DQA1
LDLR
Pakistani
Polymarker
Polymerase chain reaction
Population genetics

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10.1520/jfs14230j

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title = "Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates",

abstract = "Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.",

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author = "Tahir, {Mohammad A.} and Joseph Caruso and Bruce Budowle and Nasir Aziz and Novick, {Gabriel E.}",

year = "1997",

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doi = "10.1520/jfs14230j",

language = "English",

volume = "42",

pages = "914--918",

journal = "Journal of forensic sciences",

issn = "0022-1198",

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TY - JOUR

T1 - Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates

AU - Tahir, Mohammad A.

AU - Caruso, Joseph

AU - Budowle, Bruce

AU - Aziz, Nasir

AU - Novick, Gabriel E.

PY - 1997/9

Y1 - 1997/9

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AB - Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.

KW - Allele frequencies

KW - Arab

KW - D7S8

KW - DNA typing

KW - Forensic science

KW - GC

KW - GYPA

KW - HBGG

KW - HLA- DQA1

KW - LDLR

KW - Pakistani

KW - Polymarker

KW - Polymerase chain reaction

KW - Population genetics

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DO - 10.1520/jfs14230j

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AN - SCOPUS:0030882944

SN - 0022-1198

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ER -

Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates

Abstract

Keywords

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