Distribution of HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates

Mohammad A. Tahir, Joseph Caruso, Bruce Budowle, Nasir Aziz, Gabriel E. Novick

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.

Original languageEnglish
Pages (from-to)914-918
Number of pages5
JournalJournal of Forensic Sciences
Volume42
Issue number5
DOIs
StatePublished - Sep 1997

Keywords

  • Allele frequencies
  • Arab
  • D7S8
  • DNA typing
  • Forensic science
  • GC
  • GYPA
  • HBGG
  • HLA- DQA1
  • LDLR
  • Pakistani
  • Polymarker
  • Polymerase chain reaction
  • Population genetics

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