Disposition of remoxipride in Chinese schizophrenic patients

S. K. Lin; W. H. Chang; C. P. Chien; Y. W.F. Lam; M. W. Jann

Disposition of remoxipride in Chinese schizophrenic patients

S. K. Lin, W. H. Chang, C. P. Chien, Y. W.F. Lam, M. W. Jann

Research output: Contribution to journal › Article › peer-review

Abstract

The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.

Original language	English
Pages (from-to)	17-20
Number of pages	4
Journal	International Journal of Clinical Pharmacology and Therapeutics
Volume	34
Issue number	1
State	Published - 1996

Keywords

Pharmacokinetics
Remoxipride

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title = "Disposition of remoxipride in Chinese schizophrenic patients",

abstract = "The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.",

keywords = "Pharmacokinetics, Remoxipride",

author = "Lin, {S. K.} and Chang, {W. H.} and Chien, {C. P.} and Lam, {Y. W.F.} and Jann, {M. W.}",

year = "1996",

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T1 - Disposition of remoxipride in Chinese schizophrenic patients

AU - Lin, S. K.

AU - Chang, W. H.

AU - Chien, C. P.

AU - Lam, Y. W.F.

AU - Jann, M. W.

PY - 1996

Y1 - 1996

N2 - The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.

AB - The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.

KW - Pharmacokinetics

KW - Remoxipride

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M3 - Article

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AN - SCOPUS:0030068083

SN - 0946-1965

VL - 34

SP - 17

EP - 20

JO - International Journal of Clinical Pharmacology and Therapeutics

JF - International Journal of Clinical Pharmacology and Therapeutics

IS - 1

ER -

Disposition of remoxipride in Chinese schizophrenic patients

Abstract

Keywords

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