Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 ) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores

Elizabeth S. Childress, Joshua M. Wieting, Andrew S. Felts, Megan M. Breiner, Madeline F. Long, Vincent B. Luscombe, Alice L. Rodriguez, Hyekyung P. Cho, Anna L. Blobaum, Colleen M. Niswender, Kyle A. Emmitte, P. Jeffrey Conn, Craig W. Lindsley

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