Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents

Julie L. Engers, Alice L. Rodriguez, Leah C. Konkol, Ryan D. Morrison, Analisa D. Thompson, Frank W. Byers, Anna L. Blobaum, Sichen Chang, Daryl F. Venable, Matthew T. Loch, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte

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