Discovery of a new molecular probe ML228: An activator of the hypoxia inducible factor (HIF) pathway

Keyphrases

• Adaptive Response 33%
• Cardiovascular System Diseases 33%
• Cell-based 33%
• Cellular Response 33%
• Chemotype 33%
• Diseases of the musculoskeletal System 33%
• Gene Reporter 33%
• High-throughput 33%
• Hypoxia 33%
• Hypoxia Response 33%
• Hypoxia-inducible Factor 66%
• Hypoxia-inducible Factor Pathway 100%
• In Vitro Characterization 33%
• Ischemia 33%
• Major Organs 33%
• Medicinal Chemistry Strategies 33%
• Molecular Library 33%
• Molecular Probe 100%
• Neurological System 33%
• Organ System 33%
• Oxygen Availability 33%
• Probe Molecule 33%
• Public Health Risk 33%
• Pulmonary System 33%
• Reduced Oxygen 33%
• Renal System 33%
• Significant Pathways 33%
• Small Molecules 33%
• Transcription Factor 33%
• Triazine Scaffold 33%

Medicine and Dentistry

• Adaptive Response 20%
• Cardiovascular System 20%
• Disease 40%
• Hypoxia 40%
• Hypoxia Inducible Factor 100%
• In Vitro 20%
• Ischemia 20%
• Molecular Library 20%
• Musculoskeletal System 20%
• Organ Systems 20%
• Public Health 20%
• Renal System 20%
• Reporter Gene 20%
• Transcription Factors 20%
• Triazine 20%

Biochemistry, Genetics and Molecular Biology

• Adaptive Response 20%
• Hypoxia-Inducible Factors 100%
• Molecular Library 20%
• Molecular Probe 100%
• Reporter Gene 20%
• Small Molecule 20%
• Transcription Factors 20%