@article{3ed51c90522f4491bb9b29af0015382b,
title = "Developmental validation of 15 X chromosomal short tandem repeat markers",
abstract = "The use of X chromosomal short tandem repeat (STR) markers has been greatly increasing in the forensic setting. Using guidelines set forth previously for the validation of autosomal and Y STRs, aspects of the feasibility of routine X chromosomal STR use were evaluated. Two mini-X chromosomal STR multiplexes capable of amplifying 15 total markers were developed and utilized to determine allele nomenclature, allele/genotype frequencies, mutation rates, and linkage between markers. Additionally, a concordance study between these multiplexes and a commercially available kit was performed. Here, the authors present an overview of this extensive developmental validation study.",
keywords = "Linkage, Multiplex development, Mutation rate, Population database, Short tandem repeat, X chromosome",
author = "Diegoli, {Toni M.} and Adrian Linacre and Coble, {Michael D.}",
note = "Funding Information: Portions of this project were supported by Award No. 2011-DN-BX-K401, awarded by the National Institute of Justice, Office of Justice Programs, U.S. Department of Justice . The opinions, findings, and conclusions or recommendations expressed in this publication are those of the authors and do not necessarily reflect those of the Department of Justice. The U.S. National Institute of Justice did not have any role in study design, in collection, analysis and interpretation of data, in the writing of the report, or in the decision to submit the paper for publication. Funding Information: The authors wish to thank Minh Nguyen and the U.S. National Institute of Justice for funding, and Lt Col Laura Regan, Dr. Timothy McMahon, James Canik, Col Louis Finelli, Cynthia Thomas, and Michael Parry for administrative and logistical support. The opinions or assertions presented here are the private views of the authors and should not be construed as official or as reflecting the views of the Department of Defense, its branches, the US Army Medical Research and Materiel Command or the Armed Forces Medical Examiner System.",
year = "2013",
doi = "10.1016/j.fsigss.2013.10.074",
language = "English",
volume = "4",
pages = "e142--e143",
journal = "Forensic Science International: Genetics Supplement Series",
issn = "1875-1768",
publisher = "Elsevier Ireland Ltd",
number = "1",
}