Developing novel blood-based biomarkers for Alzheimer's disease

Heather M. Snyder, Maria C. Carrillo, Francine Grodstein, Kim Henriksen, Andreas Jeromin, Simon Lovestone, Michelle M. Mielke, Sid O'Bryant, Manual Sarasa, Magnus Sjøgren, Holly Soares, Jessica Teeling, Eugenia Trushina, Malcolm Ward, Tim West, Lisa J. Bain, Diana W. Shineman, Michael Weiner, Howard M. Fillit

Research output: Contribution to journalArticle

88 Scopus citations

Abstract

Alzheimer's disease is the public health crisis of the 21st century. There is a clear need for a widely available, inexpensive and reliable method to diagnosis Alzheimer's disease in the earliest stages, track disease progression, and accelerate clinical development of new therapeutics. One avenue of research being explored is blood based biomarkers. In April 2012, the Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened top scientists from around the world to discuss the state of blood based biomarker development. This manuscript summarizes the meeting and the resultant discussion, including potential next steps to move this area of research forward.

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalAlzheimer's and Dementia
Volume10
Issue number1
DOIs
StatePublished - Jan 2014

Keywords

  • Alzheimer's disease
  • Biomarker
  • Blood based biomarker
  • Diagnostics
  • Early detection
  • Early diagnosis

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    Snyder, H. M., Carrillo, M. C., Grodstein, F., Henriksen, K., Jeromin, A., Lovestone, S., Mielke, M. M., O'Bryant, S., Sarasa, M., Sjøgren, M., Soares, H., Teeling, J., Trushina, E., Ward, M., West, T., Bain, L. J., Shineman, D. W., Weiner, M., & Fillit, H. M. (2014). Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimer's and Dementia, 10(1), 109-114. https://doi.org/10.1016/j.jalz.2013.10.007