Abstract
Environmental metals are potentially toxic and can interfere with the metal-binding motifs of various critical proteins. This unit describes an electrophoretic method that can be used to measure the ability of a xenobiotic metal to bind a zinc-finger motif. Information gained using this protocol can lead to the identification of protein targets of metals and shed better light on their mechanisms of action.
| Original language | English |
|---|---|
| Pages (from-to) | Unit12.11 |
| Journal | Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] |
| Volume | Chapter 12 |
| Publication status | Published - Feb 2004 |
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Zawia, N. H., Basha, M. R., & Razmiafshari, M. (2004). Determining the ability of xenobiotic metals to bind a specific protein domain by electrophoresis. Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.], Chapter 12, Unit12.11.