Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding

Kyle A. Emmitte, George M. Adjebang, C. Webb Andrews, Jennifer G.Badiang Alberti, Ramesh Bambal, Stanley D. Chamberlain, Ronda G. Davis-Ward, Hamilton D. Dickson, Daniel F. Hassler, Keith R. Hornberger, Jeffrey R. Jackson, Kevin W. Kuntz, Timothy J. Lansing, Robert A. Mook, Kristen E. Nailor, Mark A. Pobanz, Stephon C. Smith, Chiu Mei Sung, Mui Cheung

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