Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

Keyphrases

• Glaucomatous Optic Neuropathy 100%
• Prodrug 100%
• Hybrid Molecules 100%
• Novel Hybrids 100%
• Sydnonimine 100%
• Topical Ocular 50%
• Nitric Oxide 50%
• Neuroprotection 50%
• IOP-lowering 50%
• Photoreceptor Cells 50%
• Bioactivity 50%
• Superoxide Dismutase 1 (SOD1) 50%
• Enzyme Level 50%
• H2O2-induced Oxidative Stress 50%
• Hybrid Compounds 50%
• Esterase 50%
• Dual-potential 50%
• Reactive Oxygen Species Scavenging 50%
• Dual-acting 50%
• Ocular Formulations 50%
• Carbamate Prodrug 50%
• Hybrid Drugs 50%
• Alkyl Carbamate 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Glaucomatous Optic Neuropathy 100%
• Prodrug 100%
• Nitric Oxide 33%
• Neuroprotection 33%
• Hydrogen Peroxide 33%
• Superoxide Dismutase 33%
• Esterase 33%
• Carbamic Acid 33%