Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations

Keith L. Monson; Jean Paul Moisan; Olivier Pascal; Michèle McSween; Dominique Aubert; Alan Giusti; Bruce Budowle; Léo Lavergne

doi:10.1159/000154274

Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations

Keith L. Monson, Jean Paul Moisan, Olivier Pascal, Michèle McSween, Dominique Aubert, Alan Giusti, Bruce Budowle, Léo Lavergne

Center for Human ID

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Allele distributions were determined for several VNTR loci in the general French Caucasian population, a French regional population from Brittany and in three French Canadian populations, residing either in Montréal or in one of two other regions in Québec. Allele distributions are highly polymorphic in all populations sampled. Despite a well-documented genetic founder effect in one of the populations, no disequilibrium was detected over all genotypes, within and between loci, for the data bases in this study. Moreover, there were no forensically significant differences observed between estimated frequencies of 1, 964 Caucasian and non-Caucasian target DNA profiles estimated in any of the groups.

Original language	English
Pages (from-to)	135-143
Number of pages	9
Journal	Human heredity
Volume	45
Issue number	3
DOIs	https://doi.org/10.1159/000154274
State	Published - 1995

Keywords

Allele frequency
Forensic
Paternity testing
Population genetics
RFLP
VNTR

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10.1159/000154274

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title = "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations",

abstract = "Allele distributions were determined for several VNTR loci in the general French Caucasian population, a French regional population from Brittany and in three French Canadian populations, residing either in Montr{\'e}al or in one of two other regions in Qu{\'e}bec. Allele distributions are highly polymorphic in all populations sampled. Despite a well-documented genetic founder effect in one of the populations, no disequilibrium was detected over all genotypes, within and between loci, for the data bases in this study. Moreover, there were no forensically significant differences observed between estimated frequencies of 1, 964 Caucasian and non-Caucasian target DNA profiles estimated in any of the groups.",

keywords = "Allele frequency, Forensic, Paternity testing, Population genetics, RFLP, VNTR",

author = "Monson, {Keith L.} and Moisan, {Jean Paul} and Olivier Pascal and Mich{\`e}le McSween and Dominique Aubert and Alan Giusti and Bruce Budowle and L{\'e}o Lavergne",

year = "1995",

doi = "10.1159/000154274",

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T1 - Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations

AU - Monson, Keith L.

AU - Moisan, Jean Paul

AU - Pascal, Olivier

AU - McSween, Michèle

AU - Aubert, Dominique

AU - Giusti, Alan

AU - Budowle, Bruce

AU - Lavergne, Léo

PY - 1995

Y1 - 1995

N2 - Allele distributions were determined for several VNTR loci in the general French Caucasian population, a French regional population from Brittany and in three French Canadian populations, residing either in Montréal or in one of two other regions in Québec. Allele distributions are highly polymorphic in all populations sampled. Despite a well-documented genetic founder effect in one of the populations, no disequilibrium was detected over all genotypes, within and between loci, for the data bases in this study. Moreover, there were no forensically significant differences observed between estimated frequencies of 1, 964 Caucasian and non-Caucasian target DNA profiles estimated in any of the groups.

AB - Allele distributions were determined for several VNTR loci in the general French Caucasian population, a French regional population from Brittany and in three French Canadian populations, residing either in Montréal or in one of two other regions in Québec. Allele distributions are highly polymorphic in all populations sampled. Despite a well-documented genetic founder effect in one of the populations, no disequilibrium was detected over all genotypes, within and between loci, for the data bases in this study. Moreover, there were no forensically significant differences observed between estimated frequencies of 1, 964 Caucasian and non-Caucasian target DNA profiles estimated in any of the groups.

KW - Allele frequency

KW - Forensic

KW - Paternity testing

KW - Population genetics

KW - RFLP

KW - VNTR

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JO - Human Heredity

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ER -

Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations

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Keywords

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