Delivery of peptides into the central nervous system

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Research into the delivery of potentially useful peptide therapeutic agents to the CNS has lagged behind the exponential growth in their discovery. There remain many problems in developing effective and safe delivery strategies, but there has been some progress in overcoming this major obstacle. The author provides an overview of those properties of the blood-brain barrier that are specific for peptides and outlines current methods addressing peptide drug delivery to the CNS.

Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalDrug Discovery Today
Volume1
Issue number4
DOIs
StatePublished - 1 Jan 1996

Fingerprint

Central Nervous System
Peptides
Blood-Brain Barrier
Growth
Research
Pharmaceutical Preparations
Therapeutics

Cite this

@article{43b30f45018847729b68071233f1b5b0,
title = "Delivery of peptides into the central nervous system",
abstract = "Research into the delivery of potentially useful peptide therapeutic agents to the CNS has lagged behind the exponential growth in their discovery. There remain many problems in developing effective and safe delivery strategies, but there has been some progress in overcoming this major obstacle. The author provides an overview of those properties of the blood-brain barrier that are specific for peptides and outlines current methods addressing peptide drug delivery to the CNS.",
author = "Laszlo Prokai",
year = "1996",
month = "1",
day = "1",
doi = "10.1016/1359-6446(96)10016-7",
language = "English",
volume = "1",
pages = "161--168",
journal = "Drug Discovery Today",
issn = "1359-6446",
publisher = "Elsevier Ltd",
number = "4",

}

Delivery of peptides into the central nervous system. / Prokai, Laszlo.

In: Drug Discovery Today, Vol. 1, No. 4, 01.01.1996, p. 161-168.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Delivery of peptides into the central nervous system

AU - Prokai, Laszlo

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Research into the delivery of potentially useful peptide therapeutic agents to the CNS has lagged behind the exponential growth in their discovery. There remain many problems in developing effective and safe delivery strategies, but there has been some progress in overcoming this major obstacle. The author provides an overview of those properties of the blood-brain barrier that are specific for peptides and outlines current methods addressing peptide drug delivery to the CNS.

AB - Research into the delivery of potentially useful peptide therapeutic agents to the CNS has lagged behind the exponential growth in their discovery. There remain many problems in developing effective and safe delivery strategies, but there has been some progress in overcoming this major obstacle. The author provides an overview of those properties of the blood-brain barrier that are specific for peptides and outlines current methods addressing peptide drug delivery to the CNS.

UR - http://www.scopus.com/inward/record.url?scp=0042040468&partnerID=8YFLogxK

U2 - 10.1016/1359-6446(96)10016-7

DO - 10.1016/1359-6446(96)10016-7

M3 - Review article

AN - SCOPUS:0042040468

VL - 1

SP - 161

EP - 168

JO - Drug Discovery Today

JF - Drug Discovery Today

SN - 1359-6446

IS - 4

ER -