Cyclic nucleotide-gated cation channel expression in embryonic chick brain

Leslie C. Timpe, Kun Lin Jin, Luis Puelles, John L.R. Rubenstein

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Cyclic nucleotide-gated cation channels mediate sensory transduction in vertebrate photoreceptors and olfactory epithelium. These channels are also present in some non-sensory cells, but little is known of their physiOlOgiCal roles outside sensory systems. Using in situ hybridization we found that cyclic nucleotide channel mRNA is expressed specifically in the embryonic chicken forebrain, thalamus, optic tectum, basal midbrain and hindbrain, as well as in the branchial arches, limb buds and skin. Cyclic nucleotide gated channels may thus contribute to development or to cellular differentiation in the brain and in other tissues.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalMolecular Brain Research
Issue number1-2
StatePublished - 20 Mar 1999


  • CNG channel
  • Chicken
  • Cyclic nucleotide-activated ion channel


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