Cutaneous blood flow increases in the rat hindpaw during dorsal column stimulation

John E. Croom; Kirk W. Barron; Margaret J. Chandler; Robert D. Foreman

doi:10.1016/0006-8993(96)00554-9

Cutaneous blood flow increases in the rat hindpaw during dorsal column stimulation

John E. Croom, Kirk W. Barron, Margaret J. Chandler, Robert D. Foreman

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The purpose of this study was to determine the optimal stimulation site and parameters that result in the greatest changes in cutaneous blood flow during dorsal column stimulation (DCS). Laser Doppler flowmetry was used to assess cutaneous blood flow changes in both rat hindpaws during DCS with a unipolar ball electrode. We found that stimulating the dorsal column at the L, spinal segment at 0.6 mA at either 25 or 50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneous blood flow increases in the rat hindpaw. In addition, the DCS response appeared to be limited primarily to the hindpaw ipsilateral to the site of DCS.

Original language	English
Pages (from-to)	281-286
Number of pages	6
Journal	Brain Research
Volume	728
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(96)00554-9
State	Published - 29 Jul 1996

Keywords

Dorsal column stimulation
Laser Doppler
Microcirculation
Skin vasodilation
Spinal cord
Spinal cord stimulation

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10.1016/0006-8993(96)00554-9

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title = "Cutaneous blood flow increases in the rat hindpaw during dorsal column stimulation",

abstract = "The purpose of this study was to determine the optimal stimulation site and parameters that result in the greatest changes in cutaneous blood flow during dorsal column stimulation (DCS). Laser Doppler flowmetry was used to assess cutaneous blood flow changes in both rat hindpaws during DCS with a unipolar ball electrode. We found that stimulating the dorsal column at the L, spinal segment at 0.6 mA at either 25 or 50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneous blood flow increases in the rat hindpaw. In addition, the DCS response appeared to be limited primarily to the hindpaw ipsilateral to the site of DCS.",

keywords = "Dorsal column stimulation, Laser Doppler, Microcirculation, Skin vasodilation, Spinal cord, Spinal cord stimulation",

author = "Croom, {John E.} and Barron, {Kirk W.} and Chandler, {Margaret J.} and Foreman, {Robert D.}",

note = "Funding Information: We gratefully thank Denise Steig and Diana Holston for technical assistance. This research was supported by Medtronics Inc., Minneapolis, MN, NIH Grant HL22732, and American Heart Association-Oklahoma affiliate.",

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AU - Croom, John E.

AU - Barron, Kirk W.

AU - Chandler, Margaret J.

AU - Foreman, Robert D.

N1 - Funding Information: We gratefully thank Denise Steig and Diana Holston for technical assistance. This research was supported by Medtronics Inc., Minneapolis, MN, NIH Grant HL22732, and American Heart Association-Oklahoma affiliate.

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N2 - The purpose of this study was to determine the optimal stimulation site and parameters that result in the greatest changes in cutaneous blood flow during dorsal column stimulation (DCS). Laser Doppler flowmetry was used to assess cutaneous blood flow changes in both rat hindpaws during DCS with a unipolar ball electrode. We found that stimulating the dorsal column at the L, spinal segment at 0.6 mA at either 25 or 50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneous blood flow increases in the rat hindpaw. In addition, the DCS response appeared to be limited primarily to the hindpaw ipsilateral to the site of DCS.

AB - The purpose of this study was to determine the optimal stimulation site and parameters that result in the greatest changes in cutaneous blood flow during dorsal column stimulation (DCS). Laser Doppler flowmetry was used to assess cutaneous blood flow changes in both rat hindpaws during DCS with a unipolar ball electrode. We found that stimulating the dorsal column at the L, spinal segment at 0.6 mA at either 25 or 50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneous blood flow increases in the rat hindpaw. In addition, the DCS response appeared to be limited primarily to the hindpaw ipsilateral to the site of DCS.

KW - Dorsal column stimulation

KW - Laser Doppler

KW - Microcirculation

KW - Skin vasodilation

KW - Spinal cord

KW - Spinal cord stimulation

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JO - Brain Research

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Cutaneous blood flow increases in the rat hindpaw during dorsal column stimulation

Abstract

Keywords

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