Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin

Keyphrases

• Transgenic 100%
• Myofibril 100%
• Myosin 100%
• Cross-bridge Kinetics 100%
• Regulatory Light Chain 100%
• Familial Hypertrophic Cardiomyopathy 100%
• Actin 50%
• Cardiac Myofibrils 33%
• Low Force 33%
• Wild Mice 16%
• Cardiac Hypertrophy 16%
• Muscle Fiber 16%
• Myosin Light Chain 16%
• Sudden Cardiac Death 16%
• Confocal Microscope 16%
• Small Populations 16%
• Muscle Contraction 16%
• Myosin Cross-bridges 16%
• Fluorescent Molecules 16%
• Single-point mutation 16%
• Downscaling 16%
• Energy Utilization 16%
• Rate of Change 16%
• Fluorescent Labeling 16%
• Sarcomeric Proteins 16%
• Impulsive Force 16%
• Orientation Change 16%
• Periodic Forcing 16%
• Cardiomyopathy mutations 16%
• Change Orientation 16%
• Actin-myosin Interaction 16%
• Kinetic Rate 16%

Biochemistry, Genetics and Molecular Biology

• Transgenics 100%
• Light Chain 100%
• Myofibril 100%
• Actin 50%
• Wild Type Mouse 16%
• Confocal Microscopy 16%
• Wild Type 16%
• Sudden Cardiac Death 16%
• Induced Mutation 16%
• Myosin Light Chain 16%
• Point Mutation 16%
• Muscle Contraction 16%
• Blood Pump 16%
• Myosin ATPase 16%