Abstract
Analytic expressions for the expectations and variance of the number of alleles with gene frequencies in a specified class are derived in the entire population as well as in a random sample of genes drawn from the population. The correlation of this quantity with heterozygosity at the locus is also obtained. The derivations are given in details for a steady state population of finite size under the infinite allele model of selectively neutral alleles. The results are extended to include weak selection pressures and non-stationarity of the population. The relevance of the correlation of heterozygosity and the number of rare alleles in connection with the neutralist-selectionist controversy is also discussed.
Original language | English |
---|---|
Pages (from-to) | 205-218 |
Number of pages | 14 |
Journal | Theoretical Population Biology |
Volume | 21 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1982 |