Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence

Kesavan Babu, Venkatesan Kathiresan, Pratibha Kumari, Sydney Newsom, Hari Priya Parameshwaran, Xiongping Chen, Jin Liu, Peter Z. Qin, Rakhi Rajan

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Medicine & Life Sciences

Chemical Compounds